Medication Management and Opioid (MMO) Initiative

In alignment with national action towards improving medication management and opioid misuse, CMS is focused on patients and improving their health outcomes, reducing unnecessary utilization, and generating cost savings for public and private payers. Our intent is to generate commitments from clinicians, practices and improvement networks and organizations to be in action by signing the MMO Pledge. This pledge will be open to all clinicians and partners to complete.

Sign the MMO Initiative Pledge!

We pledge to...

  1. Educate ourselves and our team, to refer patients to appropriate resources or implement into our practice, how to:
    • Adhere to evidence-based treatment guidelines (state and/or national).
    • Treat patient-specific pain safely and effectively.
    • Identify and treat/refer persons with substance abuse/opioid misuse issues. This should include creating opportunities to further the practice of substance use screenings and referrals.
    • Align with local pharmacies and community-based organizations that offer naloxone dispensing and education and/or provide Medication-Assisted Treatment*.
    • Coordinate with Medication Therapy Management (MTM)** services to assist with appropriate prescribing, patient education, risk stratification, and medication monitoring.
  2. Ensure persons with opioid use disorder are treated in a respectful and person-centered manner. Improvements may include:
    • Generating opportunities for patient protections providing better information about the risks and benefits of taking prescription opioids.
    • Referring to, creating, or expanding counseling and support service connections for persons and their families who have overdosed on opioids and been revived by naloxone.
    • Identifying connections to pharmacist and behavioral health resources to maximize person and family engagement with community support services.
    • Developing accountability contracts in collaboration with individuals, which includes that they only use one pharmacy and one opioid prescriber for needed pain medications.
  3. Leverage and align with existing programs and initiatives, as appropriate, to combat opioid misuse such as:
    • Relevant national and state laws, regulations, and initiatives related to opioids
    • States' Prescription Drug Monitoring Program (PDMP)
  4. Identify and report on successes and best practices and spread within CMS networks.

* Medication assisted treatment (MAT) is the use of medications in combination with counseling and behavioral therapies for the treatment of substance use disorders.
** Medication therapy management service(s) (MTMS) describe face-to-face patient assessment and intervention as appropriate, by a pharmacist, upon request. MTMS is provided to optimize the response to medications or to manage treatment-related medication interactions or complications.

Key Opioid Management Resources

The TCPI National Faculty developed a list of Opioid Medication Management Change Tactics. You can find more change tactics and resources on the TCPI Interactive Change Package!


Are you a part of a CMS Technical Assistance model like TCPI, QPP-SURs, or a QIN-QIO? Please work with your TA contact on the initiative! If you are not a member of one of these models, please contact the Solutions Center to get connected.